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Cremophor EL (Sigma Aldrich) was added to THC-EtOH solution (1 g/100 ml EtOH

DH, diastolic hypertension

They were routinely passaged by subcutaneous engraftment in Swiss Nude mice in accordance with national regulation and international guidelines [50, 54] and the rules of the French Ethics Committee: CEEA-IC (Comit dEthique en matire dexprimentation animale de lInstitut Curie, National registration number: #118)

The peptide treatment also produced dramatic improvements in a different mouse model of Alzheimers, which has a mutant form of the Tau protein that leads to neurofibrillary tangles

Figure 2 While DHAR1 has been localized to the peroxisomes, DHAR2 is cytosolic and DHAR3 encodes a dual-addressed chloroplast/mitochondrial enzyme (Figure 2)

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